Chiral synthesis of the key intermediate for 1β-methylcarbapenem antibiotics starting from (–)-carvone
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 3027-3032
- https://doi.org/10.1039/p19910003027
Abstract
A stereoselective synthesis of the key intermediate for the preparation of 1β-methylcarbapenem antibiotics was achieved by using a cyclopentanone derivative, easily derived from (–)-carvone, as a starting material.Keywords
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