Subtyping Method for Escherichia coli Shiga Toxin (Verocytotoxin) 2 Variants and Correlations to Clinical Manifestations
Top Cited Papers
- 1 June 2007
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 45 (6) , 2020-2024
- https://doi.org/10.1128/jcm.02591-06
Abstract
Shiga toxin 2 (Stx2) from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB2 operon. Of 255 strains from the Danish STEC cohort, all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2 (11 cases), subtype Stx2c (1 case), or the two combined (8 cases).Keywords
This publication has 26 references indexed in Scilit:
- VTEC O157 subtypes associated with the most severe clinical symptoms in humans constitute a minor part of VTEC O157 isolates from Danish CattleInternational Journal of Medical Microbiology, 2004
- Subtyping of virulence genes in verocytotoxin-producing Escherichia coli (VTEC) other than serogroup O157 associated with disease in the United KingdomJournal of Medical Microbiology, 2003
- Shiga Toxin–ProducingEscherichia coliin Montana: Bacterial Genotypes and Clinical ProfilesThe Journal of Infectious Diseases, 2003
- Escherichia coliHarboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical SymptomsThe Journal of Infectious Diseases, 2002
- Stx2 Subtyping of Shiga Toxin-Producing Escherichia coli Isolated from Cattle in France: Detection of a New Stx2 Subtype and Correlation with Additional Virulence FactorsJournal of Clinical Microbiology, 2001
- Heterogeneity of Shiga Toxin-Producing Escherichia coli Strains Isolated from Hemolytic-Uremic Syndrome Patients, Cattle, and Food Samples in Central FranceApplied and Environmental Microbiology, 2001
- Pheno-genotyping of verotoxin 2 (VT2)-producing Escherichia coli causing haemorrhagic colitis and haemolytic uraemic syndrome by direct analysis of patients' stoolsJournal of Medical Microbiology, 1995
- Genotyping of Shiga-like toxin genes in non-O157 Escherichia coli strains associated with haemolytic uraemic syndromeJournal of Medical Microbiology, 1995
- Variants of Shiga-like toxin II constitute a major toxin component in Escherichia coli O157 strains from patients with haemolytic uraemic syndromeJournal of Medical Microbiology, 1994
- Cloning of Genes Determining the Production of Vero Cytotoxin by Escherichia coliMicrobiology, 1985