2-Substituted 3,4-unsubstituted isoxazolin-5-ones: synthesis and comparison with the natural compounds

Abstract
Various ways to substitute the nitrogen atom of isoxazolin-5-one are described. The properties of synthetic 2-substituted 3,4-unsubstituted isoxazolin-5-ones are compared with the natural compounds. The structure of the natural 2-(2-cyanoethyl)-3-isoxazolin-5-one has been proven by establishing its identity with the synthetic compound.

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