Spinal muscular atrophy
- 1 January 2004
- journal article
- research article
- Published by Springer Nature in Current Neurology and Neuroscience Reports
- Vol. 4 (1) , 74-80
- https://doi.org/10.1007/s11910-004-0016-6
Abstract
Spinal muscular atrophy is a common genetic disease of the motor neuron (frequency of eight cases per 100,000 live births) with a high mortality during infancy and no known treatment. Death is caused by severe and progressive restrictive lung disease. New information regarding the nature and function of the SMN protein and the availability of new pharmacologic agents now make it possible to consider clinical trials in this disease. Rehabilitation and proper management of medical complications have improved both the quality and duration of life for children with spinal muscular atrophy.Keywords
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