The coexistence of psoriasis and lupus erythematosus. An analysis of 27 cases

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Abstract
From 1950 through 1975, 27 patients at the Mayo Clinic, Rochester, Minnesota, USA had coexistent psoriasis and lupus erythematosus (LE). Of these 10 had systemic LE (SLE), 13 had discoid LE and 4 had drug-induced LE or an SLE-like syndrome. The onset of psoriasis preceded LE in 10 patients and was concomitant with it in 6. Photosensitivity was noted in 23 patients. In 20 patients the lesions of psoriasis and LE remained clinically distinct. Morphologic overlap and clinical interaction occurred in 7 patients in whom the disorders were severe and complicated by a 3rd disease; this latter group had extensive psoriasis, prominent photosensitivity and a poor response to therapy.

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