Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse
- 1 August 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 310 (5979) , 650-655
- https://doi.org/10.1038/310650a0
Abstract
The major histocompatibility complex (MHC) encodes several classes of protein vital to the regulation of the immune response. Twenty-six class I genes that map to this region in the C57BL/10 mouse were isolated and these were linked into 3 gene clusters. The number of genes differs from the number found in the BALB/c strain and comparison of the organization of the class I genes in these 2 strains shows conserved regions of polymorphic genes which probably result from deletions, insertions and translocations within the MHC.This publication has 29 references indexed in Scilit:
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