Virological Investigations of Herpesvirus saimiri-lnSected Owl Monkeys

Abstract
Examination of owl monkeys with Herpesvirus saimiri (HVS) infections failed to reveal site of active viral replication. Virus was readily rescued by cocultivation from many tissues; however, infectious virus or viral antigens were not detected in these same tissues. Type-C RNA viruses were not detected using RNA-dependent DNA polymerase or group-specific radioimmunoassay techniques. Nucleic acid base analogs failed to induce type-C viruses. These data lend further support to the notion that HVS is the etiological agent of HVS-induced lymphoma in owl monkeys.

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