The inhibitory effect of some amphoteric surfactants on the irritation potential of alkylsulphates
- 1 April 1981
- journal article
- Published by Wiley in International Journal of Cosmetic Science
- Vol. 3 (2) , 57-68
- https://doi.org/10.1111/j.1467-2494.1981.tb00268.x
Abstract
Synopsis: The physico‐chemical and biological properties of an amphoteric/anionic system and its behaviour against a proteinic support have been thoroughly investigated. A considerable inhibition of adsorption of SLS (sodium lauryl sulphate) on human callus caused by the presence of definite amounts of AABet (alkyl‐amido‐betaines) in the treatment bath is observed. These physico‐chemical results are in agreement with those obtained by some in vivo biological tests. A mechanism of the process via the formation of mixed micelles is postulated emphasizing the stability of such systems as a function of pH, the influence of the chain length of the amphoteric surfactant and the molar relative ratio SLS/AABet. Consequently, our work offers the possibility of a wide applicability of the synergic mixtures of both types of surfactants to inhibit considerably skin irritation of cosmetic finished products.Keywords
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