EFFECT OF THIOPENTONE ON MYOCARDIAL FUNCTION
Open Access
- 1 September 1977
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 49 (9) , 865-870
- https://doi.org/10.1093/bja/49.9.865
Abstract
In a canine preparation designed to separate myocardial from peripheral cardiovascular effects of the drug, it was found that thiopentone produced minimal depression of the heart. Only in much greater concentrations was significant depression found. It is concluded that the cardiovascular effects of thiopentone i.v. are not a direct effect on the heart.This publication has 3 references indexed in Scilit:
- HEMODYNAMIC CHANGES DURING THIOPENTAL ANESTHESIA IN HUMANS: CARDIAC OUTPUT, STROKE VOLUME, TOTAL PERIPHERAL RESISTANCE, AND INTRATHORACIC BLOOD VOLUME 12Journal of Clinical Investigation, 1955
- THE EFFECT OF CYCLOPROPANE, DIETHYL ETHER, NITROUS OXIDE, THIOPENTAL, AND HYDROGEN ION CONCENTRATION ON THE MYOCARDIAL FUNCTION OF THE DOG HEART-LUNG PREPARATION1955
- CARDIOVASCULAR TOXICITY OF THIOBARBITURATES - COMPARISON OF THIOPENTAL AND 5-ALLYL-5-(1-METHYLBUTYL)-2-THIOBARBITURATE (SURITAL) IN DOGS1949