Organocatalytic Enantioselective Synthesis of α-Hydroxy Phosphonates
- 16 May 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 128 (23) , 7442-7443
- https://doi.org/10.1021/ja062091r
Abstract
Tertiary α-hydroxy phosphonates have been synthesized in good yields and high enantiomeric purity (up to 99% ee) through a novel l-proline-catalyzed cross aldol reaction of α-keto phosphonates and ketones.Keywords
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