Analysis of serotype AD strains from F1 progenies between urease-positive- and negative-strains of Cryptococcus neoformans.
Open Access
- 1 January 2003
- journal article
- Published by The Japanese Society for Medical Mycology in Japanese journal of medical mycology
- Vol. 44 (4) , 293-297
- https://doi.org/10.3314/jjmm.44.293
Abstract
Cryptococcus neoformans is a pathogenic basidiomycete with a defined sexual cycle involving mating between haploid yeast cells with a transient diploid state. We examined F1 progeny from a crossing between the urease-negative strain (environmental isolate, serotype A, mating type α, haploid) and a tester strain (B 3502 from NIH of USA; urease-positive, serotype D, mating type a, haploid) for serotype, mating type, ploidy and urease activity, and performed partial sequencing of the urease gene. Phenotypes of the F1 progeny and results of SSCP analyses suggested that the serotype AD strain of the F1 progeny is a hybrid of the parental serotype A and D strains.Keywords
This publication has 0 references indexed in Scilit: