Changing patterns of invasive Haemophilus influenzae disease in England and Wales after introduction of the Hib vaccination programme
- 20 January 1996
- Vol. 312 (7024) , 160-161
- https://doi.org/10.1136/bmj.312.7024.160
Abstract
The case definition was a systemic infection in which culture of normally sterile body fluid revealed H influenzae, or the organism was detected by antigen to H influenzae type b. Organisms were identified and typed at the reference laboratories using both type specific antisera and a polymerase chain reaction method.1 Brief clinical details were also collected. The results for the first two years of the survey showed that most H influenzae infections were due to type b, presented as meningitis, and occurred in children under 5,2 suggesting that mass vaccination of infants should achieve a rapid change in the pattern of invasive H influenzae infections.Keywords
This publication has 3 references indexed in Scilit:
- Epidemiology of invasiveHaemophilus influenzaeinfections in England and Wales in the pre-vaccination era (1990–2)Epidemiology and Infection, 1995
- Decline of Childhood Haemophilus influenzae Type b (Hib) Disease in the Hib Vaccine EraJAMA, 1993
- Rapid disappearance of Haemophilus influenzae type b meningitis after routine childhood immunisation with conjugate vaccinesThe Lancet, 1992