t(10;16)(q22;p13) and MORF‐CREBBP fusion is a recurrent event in acute myeloid leukemia
- 30 January 2003
- journal article
- case report
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 36 (4) , 402-405
- https://doi.org/10.1002/gcc.10174
Abstract
Recently, it was shown that t(10;16)(q22;p13) fuses the MORF and CREBBP genes in a case of childhood acute myeloid leukemia (AML) M5a, with a complex karyotype containing other rearrangements. Here, we report a new case with the MORF‐CREBBP fusion in an 84‐year‐old patient diagnosed with AML M5b, in which the t(10;16)(q22;p13) was the only cytogenetic aberration. This supports that this is a recurrent pathogenic translocation in AML.Keywords
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