In vitro antiviral activity on dengue virus of marine natural products
- 6 February 1998
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 54 (2) , 167-170
- https://doi.org/10.1007/s000180050138
Abstract
Metabolites isolated from marine invertebrates, callipeltin A 1, crambescidin 2, ptilomycalin A 3, celeromycalin 4, gymnochrome B 5, gymnochrome D 6 and isogymnochrome D 7 previously shown bioactive on either herpes simplex virus 1 (2, 3, 4) or human immunodeficiency virus (1, 5, 6, 7), were tested on a new in vitro bioassay using the dengue virus 1. Only gymnochrome D and isogymnochrome D isolated from the living fossil crinoid Gymnocrinus richeri are highly potent dengue antiviral agents.Keywords
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