Successful treatment of nephrogenic fibrosing dermopathy in a kidney transplant recipient with photodynamic therapy

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Abstract
Nephrogenic fibrosing dermopathy (NFD) was first described by Cowper et al. [1] as a cutaneous fibrosing disorder associated with renal dysfunction. In the last 3 years there has been a growing body of literature regarding NFD. Clinically, skin is thickened or oedematous with indurated papules and plaques. The pathogenesis of NFD is largely unknown. Several authors have discussed a reaction against the PVC materials used in dialysis, but NFD has also occurred in patients without dialysis [2–4 ]. Spontaneous healing of NFD has not been documented previously; however restitutio ad integrum after improvement of the renal situation has been reported [2]. The therapy of NFD has to be regarded as difficult and, to date, only experimental therapies have been published. We report the first case of successful treatment of NFD following kidney transplantation.

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