Salicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein-β Binding via a Common Signaling Pathway
Open Access
- 1 December 2002
- journal article
- Published by Elsevier
- Vol. 277 (51) , 49304-49310
- https://doi.org/10.1074/jbc.m205030200
Abstract
No abstract availableKeywords
This publication has 27 references indexed in Scilit:
- The Induction of Cyclooxygenase-2 mRNA in Macrophages Is Biphasic and Requires both CCAAT Enhancer-binding protein β (C/EBPβ) and C/EBPδ Transcription FactorsPublished by Elsevier ,2001
- Selective Suppression of CCAAT/Enhancer-binding Protein β Binding and Cyclooxygenase-2 Promoter Activity by Sodium Salicylate in Quiescent Human FibroblastsJournal of Biological Chemistry, 2001
- Phosphorylation of Rat Serine 105 or Mouse Threonine 217 in C/EBPβ Is Required for Hepatocyte Proliferation Induced by TGFαMolecular Cell, 1999
- Transcriptional Regulation of the Cyclooxygenase-2 Gene by Diverse Ligands in Murine OsteoblastsBiochemical and Biophysical Research Communications, 1999
- Salicylate Is a Transcriptional Inhibitor of the Inducible Nitric Oxide Synthase in Cultured Cardiac FibroblastsPublished by Elsevier ,1996
- Transcriptional Regulation of Human Prostaglandin-endoperoxide Synthase-2 Gene by Lipopolysaccharide and Phorbol Ester in Vascular Endothelial CellsJournal of Biological Chemistry, 1995
- Requirement for Transcription Factor IRF-1 in NO Synthase Induction in MacrophagesScience, 1994
- Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domainNature, 1993
- Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.The Journal of Experimental Medicine, 1993
- Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβScience, 1992