Plasmodium knowlesi infections in a small number of non-immune natural hosts (Macaca fascicularis) and in rhesus monkeys (M. mulatta)
- 31 January 2010
- journal article
- research article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 104 (1) , 75-77
- https://doi.org/10.1016/j.trstmh.2009.05.017
Abstract
The natural host of Plasmodium knowlesi is the kra monkey, Macaca fascicularis, but this parasite, initially mistaken for P. malariae, is now infecting humans in some areas of Southeast Asia. Here we present data from experiments performed in the 1970s in which sera from a few naive M. fascicularis, taken in the course of a first infection, exhibited rapidly rising inhibition of in vitro replication of P. knowlesi. The results were compared with sera from P. knowlesi-infected rhesus monkeys that usually die if left untreated.Keywords
This publication has 2 references indexed in Scilit:
- Knowlesi malaria: newly emergent and of public health importance?Trends in Parasitology, 2008
- Rhesus and Crab-Eating Macaques: Intergradation in ThailandScience, 1964