The effect of calcium dobesilate on albumin leakage of the conjunctival vessels

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Abstract
Calcium dobesilate significantly reduced the leakage of serum albumin in the tearfluid in patients with chronic inflammatory reactions of the conjunctiva. In the majority of cases reduction of serum albumin concentration in the tear-fluid was treatment related. The marked increase in tear albumin concentration after treatment, found in two cases, was caused by a sharp increase in the inflammatory reaction due to an exacerbation of the underlying disease during the trial period. No relation was found between improvement of symptoms as reported by the patients and alterations in serum albumin concentrations.