Mapping of the Fv‐4 mouse gene controlling resistance to murine leukemia viruses

Abstract
Fv-4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre-1 (prealbumin) and Igh-1 (immunoglobulin heavy-chain constant region) loci on chromosome 12 in mice. The gene order was Fv-4-Pre-1-Igh-1, and the estimated frequency of recombination between Fv-4 and Pre-1 was about 20%.