Untersuchungen zur Biogenese des Erythromycins
Open Access
- 1 September 1960
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 15 (9) , 560-568
- https://doi.org/10.1515/znb-1960-0904
Abstract
After addition of propionic acid-[1-14C-3-T] to cultures of Streptomyces erythreus the 14C/T ratio in the isolated erythromycin was determined and Kuhn -Roth oxidation was carried out to determine the location of the 14C and T activity in the molecule. The results prove that the lactone ring of erythromycin is derived from propionate units. Possibly propionic acid also plays a part in the biosynthesis of cladinose.Keywords
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