Pharmacologic Vasodilation

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Abstract
In 19 patients with ischemic disease of the lower extremities, blood flow and skin temperature was measured in the foot after combined i.v. vasodilator and placebo infusion. All patients were covered with a blanket during both types of infusion. A significant rise in the foot and skin temperature was observed during both types of infusions and the effect was significantly higher during administration of vasodilators. The elevation of the foot blood flow persisted for 1 to 2 h after the termination of the infusion. [Vasodilator drugs are widely used but they can increase skin blood flow in normal and ischemic limbs. The duration of the vasodilator effect was studied.].