Ultraviolet Sensitivity of Escherichia coli Containing Heat-Inducible λ Prophages
- 10 July 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3628) , 175-176
- https://doi.org/10.1126/science.145.3628.175
Abstract
The c1-t mutants of bacteriophage λ can form prophage at 36°C but cause lysis of sensitive bacteria at temperatures above 42°C. Growth of cultures at 42° to 46°C induces prophage replication and lysis in Escherichia coli K12 (λ c1-t); lysogenic strains containing wild-type prophage are not induced to lyse at these temperatures. Heat induction is prevented by chloramphenicol. Strains containing heatinducible prophage are much more sensitive to killing by ultraviolet light than is K12 (λ+).Keywords
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- Genetic regulatory mechanisms in the synthesis of proteinsPublished by Elsevier ,2010