Abstract
The matrix of four columns and three rows combines public health concepts of host-agent-environment as targets of change with the concepts of primary, secondary, and tertiary prevention.3, 4 More specifically, the factors defined by the columns in the matrix refer to the interacting factors that contribute to the injury process (see tables 1 and 2). The host column refers to the person at risk of injury. The agent of injury is energy (for example mechanical, thermal, electrical) that is transmitted to the host through a vehicle (inanimate object) or vector (person or other animal). Physical environments include all the characteristics of the setting in which the injury event takes place (for example a roadway, building, playground, or sports arena). Social and legal norms and practices in the culture are referred to as the social environment. Examples include norms about child discipline or alcohol consumption or policies about licensing drivers or sales of firearms.

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