Tropomyosin Inhibits the Interaction of F-Actin and Filamin1
- 1 October 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 84 (4) , 1017-1019
- https://doi.org/10.1093/oxfordjournals.jbchem.a132184
Abstract
The value of flow birefringence of F-actin was greatly decreased by filamin due to precipitate formation. This precipitate could be dispersed into birefringent filaments by sonication. Tropomyosin inhibited precipitation of F-actin induced by filamin, and no decrease in birefringence occurred when filamin was added to tropomyosin-bound F-actin. Hence it appears that filamin acts on F-actin in non-muscle cells similarly to α-actinin.This publication has 2 references indexed in Scilit:
- Interaction of filamin with f-actin in solution.Proceedings of the National Academy of Sciences, 1977
- Two general classes of cytoplasmic actin filaments in tissue culture cells: The role of tropomyosinJournal of Supramolecular Structure, 1976