Ventricular Tachycardia Associated With Myocardial Infarct Scar

Abstract
Background— The overactivity of ergoreceptors (intramuscular afferents sensitive to products of skeletal muscle work) may be responsible for the abnormal responses to exercise and symptoms of exercise intolerance in chronic heart failure (CHF); however, little is known of the chemical nature of the stimuli involved. We investigated biochemical factors (H+, V̇co2, V̇o2, Hco3, K+, phosphate, lactate, PGE2, PGF, and bradykinin) potentially involved in ergoreceptor activation.