Microscopically controlled surgery for extramammary Paget's disease

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Abstract
In 5 cases of extramammary [skin] Paget''s disease (EMPD), the neoplasms were removed under complete microscopical control by a fixed-tissue chemosurgical technique in 1 case and fresh-tissue technique in 4 cases. In each lesion there were histologically involved areas extending several centimeters into clinically normal-appearing skin. All patients have been free of the disease for periods from 4 mo. to 9 yr. Conventional surgery has been reported with a recurrence rate of 44%. Microscopically controlled surgery offers the most reliable method of removing all of the neoplastic tissue EMPD and preserves as much normal tissue as possible.