A Cytoplasmic Factor Promoting Oocyte Maturation: Its Extraction and Preliminary Characterization
- 26 March 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 191 (4233) , 1266-1268
- https://doi.org/10.1126/science.1083070
Abstract
Cytoplasm of maturing amphibian oocytes possesses a factor that induces germinal vesicle breakdown. This factor was extracted from Rana pipiens eggs and assayed by microinjection in Xenopus laevis oocytes. The activity of this factor is Mg-dependent, Ca-sensitive, and associated with heat-labile protein. Centrifugation on a sucrose density gradient revealed that the factor exists in three different molecular sizes.This publication has 23 references indexed in Scilit:
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