Accumulation of radioiodinated tyrosine derivatives in the adrenal medulla and in melanomas
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in European Journal of Nuclear Medicine and Molecular Imaging
- Vol. 4 (3) , 179-186
- https://doi.org/10.1007/bf00620482
Abstract
Because tyrosine and dopa can be regarded as precursors of adrenomedullary hormones and melanin, radioiodinated derivatives of these compounds were tested for their accumulation in the adrenal medulla and in melanomas of various animal species. The highest level of accumulation in the adrenal medulla was attained in mice and rats with iodinated β-hydroxy-α-methyltyramine, and in melanomas of mice with iodinated α-methyltyrosine. The results could not be reproduced to the same extent in other species.Keywords
This publication has 17 references indexed in Scilit:
- Concentration of dopamine analogs in the adrenal medulla.1975
- Labeled dopamine concentration in pheochromocytomas.1973
- Synthesis and preliminary evaluation in animals of carrier-free 11C-1-dopamine hydrochloride: X.1973
- AUTORADIOGRAPHIC STUDIES ON THE ROLE OF ADRENALINE IN STRESS BY USING H3 ADRENALINEAmerican Journal of Roentgenology, 1973
- Tumor Localizing Agents VIIIJournal of Pharmaceutical Sciences, 1968
- Visualizing human malignant melanoma and metastases. Use of chloroquine analog tagged with iodine 125.1968
- Visualizing Human Malignant Melanoma and MetastasesPublished by American Medical Association (AMA) ,1968
- Melanin Binding Properties of Iodoquine**From the Department of Dermatology, Stanford University School of Medicine, Palo Alto, California.Journal of Investigative Dermatology, 1968
- RADIOACTIVITY FROM LABELED PRECURSORS OF MELANIN IN MICE AND HAMSTERS WITH MELANOMAS1967
- Einfluß des Dopa-Decarboxylase-Hemmers α-Methyl-Dopa auf die Umwandlung von Dopa in Melanin und BrenzcatechinamineNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1963