Distinguishing Characteristics of the Interferon Responses of Primary and Continuous Mouse Cell Cultures
Open Access
- 1 October 1971
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 13 (1) , 35-50
- https://doi.org/10.1099/0022-1317-13-1-35
Abstract
Cultures of primary mouse kidney cells and those of L cells produced interferon in response to Newcastle disease virus and polyinosinic-polycytidylic acid. The interferon produced by L cells was made between 8 and 18 hr post-inoculation irrespective of the inducer. The interferon produced by mouse kidney cell cultures in response to Newcastle disease virus was made between 8 and 18 hr while that produced in response to polyinosinic-polycytidylic acid was made between 2 and 12 hr.Keywords
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