Trials within trials? Researcher, funder and ethical perspectives on the practicality and acceptability of nesting trials of recruitment methods in existing primary care trials
Open Access
- 30 April 2010
- journal article
- Published by Springer Nature in BMC Medical Research Methodology
- Vol. 10 (1) , 38
- https://doi.org/10.1186/1471-2288-10-38
Abstract
Trials frequently encounter difficulties in recruitment, but evidence on effective recruitment methods in primary care is sparse. A robust test of recruitment methods involves comparing alternative methods using a randomized trial, 'nested' in an ongoing 'host' trial. There are potential scientific, logistical and ethical obstacles to such studies.Keywords
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