Hyperphenylalaninemia: Disaggregation of Brain Polyribosomes in Young Rats
- 3 April 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3927) , 129-130
- https://doi.org/10.1126/science.168.3927.129
Abstract
A single injection of l-phenzylalanine in 7-day-old rats produtced disaggregation of brain polyribosomties and inhibition of in vitro protein synthesis in cell-free systems prepared from brain. Liver polyribosomes and in vitro protein synthesis in hepatic systems were not affected. In 4-week-old rats these effects on brain protein synthesis did not occur.Keywords
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