STUDIES OF LUNG VOLUMES AND INTRAPULMONARY MIXING: NOTES ON OPEN-CIRCUIT METHODS, INCLUDING USE OF A NEW PIVOTED TYPE GASOMETER FOR LUNG CLEARANCE STUDIES

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Abstract
The extension of open-circuit methods of measuring lung vols. to a study of lung clearance rates requires physical modifications which have been embodied in 2 exptl. methods referred to as "end-point sampling" and "serial sampling." The former can be carried out with modified standard equipment but is laborious. The latter requires a specially designed gasometer of small internal and external dead-space, a gas mixer and attachments for rapid sampling of the mixed expired gas at frequent intervals. A pivoted type gasometer constructed for the serial sampling method is descr. The gasometer is also suitable for standard spirometric studies. Exptl. procedures are descr.