Abstract
Although the hormone leptin hasn9t turned out to be a "magic bullet" for obesity, its discovery has stimulated basic lab research which has been sketching out a much clearer picture of just how the body controls its weight. Researchers have identified a wealth of molecules involved in weight regulation, some of which cooperate with leptin to suppress appetite, while others blunt the hormone9s fat-busting effects. Combining all these new molecular actors together in one leptin-conducted performance will be a daunting task, but they are already providing new targets for antiobesity drugs.

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