Tracing Leptin's Partners in Regulating Body Weight
- 10 March 2000
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 287 (5459) , 1738-1741
- https://doi.org/10.1126/science.287.5459.1738
Abstract
Although the hormone leptin hasn9t turned out to be a "magic bullet" for obesity, its discovery has stimulated basic lab research which has been sketching out a much clearer picture of just how the body controls its weight. Researchers have identified a wealth of molecules involved in weight regulation, some of which cooperate with leptin to suppress appetite, while others blunt the hormone9s fat-busting effects. Combining all these new molecular actors together in one leptin-conducted performance will be a daunting task, but they are already providing new targets for antiobesity drugs.Keywords
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