ESTEROLYTIC ACTIVITY OF ELASTASE
- 1 October 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 64 (2) , 683-685
- https://doi.org/10.1073/pnas.64.2.683
Abstract
The esters of L-alanine were found to be excellent substrates for elastase. The pH-dependence study using two methyl esters of this substrate showed the participation in the mechanism of an ionizing group with an apparent pK of 6.85 and a decrease of the activity at pH's greater than 10 (that could correspond to an apparent pK of 11.4).Keywords
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