The Ubiquitin Ligase Itch Is Auto-ubiquitylated in Vivo and in Vitro but Is Protected from Degradation by Interacting with the Deubiquitylating Enzyme FAM/USP9X
Open Access
- 1 December 2006
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 281 (50) , 38738-38747
- https://doi.org/10.1074/jbc.m605959200
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL TurnoverCell, 2006
- Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion proteinOncogene, 2004
- The HECT Domain Ligase Itch Ubiquitinates Endophilin and Localizes to the trans-Golgi Network and Endosomal SystemJournal of Biological Chemistry, 2004
- WW Domain HECT E3s Target Cbl RING Finger E3s for Proteasomal DegradationJournal of Biological Chemistry, 2003
- Conjugation and deconjugation of ubiquitin regulating the destiny of proteinsExperimental & Molecular Medicine, 2003
- Receptor downregulation and multivesicular-body sortingNature Reviews Molecular Cell Biology, 2002
- Ubiquitin, proteasomes, and the regulation of intracellular protein degradationPublished by Elsevier ,2002
- Mechanisms Underlying UbiquitinationAnnual Review of Biochemistry, 2001
- Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin LigaseJournal of Biological Chemistry, 2000
- Ubiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated EndocytosisCell, 1996