BROMIDE INTOXICATION

12 July 1930

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 95 (2) , 94-96
https://doi.org/10.1001/jama.1930.02720020010003

Abstract

On account of the widespread use of bromide in neuropsychiatric disorders, and because of the fact that most "patent" remedies recommended for their sedative effect contain this drug, bromide intoxication is a very common syndrome. During the past three months we have observed seven cases. Dr. Franklin G. Ebaugh, director of the Colorado State Psychopathic Hospital, in a recent communication stated that of 500 admissions 7 per cent were cases of bromide intoxication. At the Henry Phipps Institute, Diethelm¹reports that 2 per cent of the patients admitted show a toxic reaction from taking bromides. Wuth²found 20 cases out of 238 admissions. We feel certain that there are many more unreported cases that go unrecognized. The frequent occurrence of the condition is accounted for by the fact that there is a tendency for bromide to be retained in the body instead of being eliminated rapidly. If the

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