THE INFLUENCE OF COBAMIDES ON THE ENDOGENOUS AND EXOGENOUS RESPIRATION OF A MARINE BACTERIUM
- 1 December 1962
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 8 (6) , 861-867
- https://doi.org/10.1139/m62-113
Abstract
The oxidation of propionate, isobutyrate, valerate, isoleucine, and valine as well as the endogenous respiration of a B12-dencient marine bacterium was stimulated by the addition of vitamin B12to washed cell suspensions. The B12analog, 2-methyladenylcobamide cyanide, also stimulated endogenous respiration, but cobinamide was inactive. During autorespiration ammonia was continuously evolved by the cells indicating the presence of a nitrogenous endogenous substrate. When vitamin B12was supplied to the cells, the ammonia evolved was decreased, while the rate of oxygen uptake was increased. The possible involvement of cobamide coenzymes is discussed in relation to these findings.This publication has 7 references indexed in Scilit:
- Effect of vitamin B12 and analogs on the respiration of a marine bacteriumArchives of Biochemistry and Biophysics, 1962
- METHYLMALONYL ISOMERASE, II. PURIFICATION AND PROPERTIES OF THE ENZYME FROM PROPIONIBACTERIAProceedings of the National Academy of Sciences, 1961
- MAMMALIAN METHYLMALONYL ISOMERASE AND VITAMIN B 12 COENZYMESProceedings of the National Academy of Sciences, 1960
- Vitamin B12 and propionate metabolismBiochemical and Biophysical Research Communications, 1959
- COENZYME A THIOL ESTERS OF ISOBUTYRIC, METHACRYLIC, AND β-HYDROXYISOBUTYRIC ACIDS AS INTERMEDIATES IN THE ENZYMATIC DEGRADATION OF VALINEJournal of Biological Chemistry, 1957
- The effect of B12 on enzyme activity in E. coli mutant 113-3Archives of Biochemistry and Biophysics, 1956