BACTERICIDAL ACTION OF MERCUROCHROME-220 SOLUBLE AND IODINE SOLUTIONS IN SKIN DISINFECTION

8 September 1928

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 91 (10) , 704-708
https://doi.org/10.1001/jama.1928.02700100016005

Abstract

The experiments here reported form a part of a general investigation undertaken at the suggestion of the medical supply division of the army with a view to securing, if possible, an antiseptic procurable from our own natural resources and possessing the same germicidal effectiveness as iodine, or greater effectiveness, for the disinfection of local tissues, including the unbroken skin, open wounds and mucous membranes. The phase of the general search for effective iodine substitutes considered in this paper deals with the relative bactericidal effectiveness of various recommended mercurochrome-220 soluble and iodine solutions in disinfection of the unbroken skin. Mercurochrome was selected for these experiments mainly because of its widespread use as a general antiseptic in place of iodine and because of the various favorable reports regarding its germicidal qualities recorded in the recent medical literature. Tinker and Sutton¹reported that both mercurochrome and iodine solutions (5 per cent alcoholic)

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