γ-Glutamyl Transpeptidase Activity and Its Serial Measurement in Differentiation Between Extrahepatic Biliary Atresia and Neonatal Hepatitis
- 1 April 1985
- journal article
- research article
- Published by Wiley in Journal of Pediatric Gastroenterology and Nutrition
- Vol. 4 (2) , 208-213
- https://doi.org/10.1097/00005176-198504000-00009
Abstract
The liver functions of 17 babies with extrahepatic biliary atresia (EHBA) and 91 babies with neonatal hepatitis (NNH) were analyzed. The serum .gamma.-glutamyl transpeptidase (GGTP) level and its rate of rise were significantly higher in the EHBA group. Both cross-sectional and longitudinal studies showed a positive correlation between the GGTP activity and the duration of the disease. The diagnostic accuracy is 79% for EHBA and 95% for NNH. It is suggested that GGTP and its rate of rise are the most important biochemical parameters in the differential diagnosis of these 2 diseases.This publication has 2 references indexed in Scilit:
- ReplyThe Journal of Pediatrics, 1980
- A diagnostic approach to prolonged obstructive jaundice by 24-hour collection of duodenal fluidThe Journal of Pediatrics, 1979