Nicotinic Acid—Tryptophan Nutrition and Immunologic Implications in Young Swine

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Abstract
The efficacy of L- and DL-tryptophan conversion to nicotinic acid was measured in young swine receiving corn-based diets formulated just to meet the requirement for tryptophan. The addition of either 0.01% L- or DL-tryptophan or 13.2 ppm nicotinic acid significantly increased rate of gain and improved gain/feed ratio compared to that of pigs fed the unsupplemented diet. Rate of gain and gain/feed were not enhanced by substituting wheat or oats for corn. However, adding 5% wheat bran to the corn diet resulted in performance equal to that from supplemental nicotinic acid. Pigs deficient in nicotinic acid or tryptophan exhibited immunologic responses and serum protein values equivalent to pigs on the complete diet.

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