Artificial Electron Carriers for Preparative Biocatalytic Redox Reactions Forming Reversibly Carbon Hydrogen Bonds with Enzymes Present in Strict or Facultative Anaerobes
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in Biocatalysis and Biotransformation
- Vol. 12 (1) , 1-26
- https://doi.org/10.3109/10242429508998147
Abstract
The application of various artificial electron mediators in combination with redox enzymes present in anaerobically grown cells is described. Examples include viologens of different redox potential, cobalt complexes, anthraquinones, phenoxazines, phenazines and others. The regeneration of the reduced or oxidised mediators by various methods is discussed, with hydrogen gas, carbon monoxide, formate or a cathode as electron donors, and dimethylsulphoxide, quinones, oxygen or an anode as electron acceptors. The enzymes used, usually in the form of resting cells or crude cell extracts of clostridia or Proteus species are mostly reversible. Examples for preparative reductions as well as for dehydrogenations are given.Keywords
This publication has 60 references indexed in Scilit:
- Formiat-getriebene, nicht-enzymatische NAD(P)H-Regeneration bei der durch Alkohol-Dehydrogenasen katalysierten stereoselektiven Reduktion von 4-Phenyl-2-butanonAngewandte Chemie, 1992
- Reduction of NAD(P)+ by electrochemically driven FADH2 and FMNH2Bioelectrochemistry and Bioenergetics, 1992
- Properties and mechanistic aspects of newly found redox enzymes from anaerobes suitable for bioconversions on preparatory scalePublished by Walter de Gruyter GmbH ,1992
- Direct electron transfer from modified glassy carbon electrodes carrying covalently immobilised mediators to a dissolved viologen accepting pyridine nucleotide oxidoreductase and dihydrolipoamide dehydrogenaseBioelectrochemistry and Bioenergetics, 1991
- Direct Electron Transfer between Carbon Electrodes, Immobilized Mediator and an Immobilized Viologen‐accepting Pyridine Nucleotide OxidoreductaseAngewandte Chemie International Edition in English, 1990
- Mitochondria catalyze the reduction of NAD by reduced methylviologenFEBS Letters, 1987
- Electron transfers in chemistry and biologyBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1985
- Effect of pH on H-2H exchange, H2 production and H2 uptake, catalysed by the membrane-bound hydrogenase of Paracoccus denitrificansBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1982
- Mediator compounds for the electrochemical study of biological redox systems: a compilationAnalytica Chimica Acta, 1982
- On the hydrogen-deuterium exchange reaction catalyzed by the soluble hydrogenase from Alcaligenes eutrophus H16 in the free and immobilized stateBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982