Biosynthetic Capacities of Actinomysetes. No.26. Endophenazines A-D, New Phenazine Antibiotics from the Arthropod Associated Endosymbiont Streptomyces anulatus. I. Taxonomy, Fermentation, Isolation and Biological Activities.
- 1 January 2002
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 55 (9) , 794-800
- https://doi.org/10.7164/antibiotics.55.794
Abstract
Four new members of the phenazine family, endophenazines A-D, and the already known phenazine-1-carboxylic acid (tubermycin B) were detected in the culture broth of various endosymbiotic Streptomyces anulatus strains by chemical screening in a combination of TLC-staining reagents and HPLC-diode array analysis. The endosymbiotic strains were isolated from four different arthropod hosts at various sites. The new phenazine compounds showed antimicrobial activities against Gram-positive bacteria and some filamentous fungi, and herbicidal activity against Lemna minor (duckweed).Keywords
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