Anti-carcinogenic activity of d-limonene during the initiation and promotion/progression stages of DMBA-induced rat mammary carcinogenesis
- 1 January 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 9 (2) , 331-332
- https://doi.org/10.1093/carcin/9.2.331
Abstract
D-Limonene was found to be effective in reducing the average number of rat mammary carcinomas that developed in 7,12-dimeihylbenz[a]anthracene-treated rats when the terpene was fed during the initiation or during the promotion/progression stage of carcinogenesis. The time to the appearance of the first tumor was extended only when d-limonene was fed during the initiation stage. These effects could not be attributed to changes in mammary-relevant endocrine functions.This publication has 3 references indexed in Scilit:
- Regression of Rat Primary Mammary Tumors Following Dietary d-Limonene2JNCI Journal of the National Cancer Institute, 1986
- Inhibition of DMBA-induced mammary cancer by the monoterpene d-limoneneCarcinogenesis: Integrative Cancer Research, 1984
- The use ofd-limonene preparation as a dissolving agent of gallstonesDigestive Diseases and Sciences, 1976