A major metabolite of Δ1-tetrahydrocannabinol reduces its cataleptic effect in mice
- 1 April 1987
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 43 (4) , 402-403
- https://doi.org/10.1007/bf01940427
Abstract
The results described here demonstrate that THC-induced catalepsy in mice can be substantially inhibited by the prior administration of Δ1-THC-7-oic acid, the major metabolite of THC in most species including humans. This raises the possibility that the intensity and duration of action of THC may depend to a large degree on the levels of this metabolite at the sites of action.This publication has 10 references indexed in Scilit:
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