CHOLECYSTOGRAPHY

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Abstract
In previous publications,1we have established the fact that cholecystography is possible in the living human subject. By this we mean making the gallbladder opaque to the roentgen ray by the injection of certain substances into the blood stream which are largely excreted into the bile. We have also called attention to the criteria that determine a normal or pathologic gallbladder when examined in this way. In our earlier investigations, we used for study salts of tetraiodophenolphthalein and tetrabromphenolphthalein. Both of these substances gave excellent shadows. Since that time we have examined twenty-eight other substances, six of which have also made the gallbladder visible after intravenous injection. Theoretically, any substance containing a metal or a bromin or iodin atom would make the gallbladder visible if it were in sufficient concentration in the gallbladder. It is therefore apparent that a vast number of possibilities exist of finding chemical substances which

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