SIALIC ACID CONTENT AND SPERM PENETRATION OF CERVICAL MUCUS IN RELATION TO TOTAL URINARY OESTROGEN EXCRETION AND PLASMA PROGESTERONE LEVELS IN OVULATORY WOMEN

Abstract
Daily measurements of sialic acid content and sperm penetration into the cervical mucus were related to the total urinary oestrogen excretion and plasma progesterone levels during one ovulatory cycle in six regularly menstruating women. In four women of known fertility and in one normally menstruating woman the peak in sperm penetration and the dip in sialic acid content occurred almost simultaneously with the ovulatory oestrogen peak in urine and preceded the probable day of ovulation by one day. In one woman who was barren for several years the steroid patterns were normal but the peak in sperm penetration and the dip in sialic acid content occurred one day after ovulation. The possible significance of this observation and other data are discussed.

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