PCR for Detection of Oseltamivir Resistance Mutation in Influenza A(H7N9) Virus
Open Access
- 1 May 2014
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 20 (5) , 847-849
- https://doi.org/10.3201/eid2005.131364
Abstract
Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.Keywords
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