Blood Coagulation Factors I, II, V, VII, VIII, IX, X, XI and XII in Twins

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Abstract
Sources of variation in blood clotting factors I, II, V, VII, VIII, IX, X, XI and XII have been investigated in a series of adult male twin pairs. Estimates of components of variation are presented, together with other sample statistics. The study emphasizes the importance of technical and experimental vari ation in the determination of the levels of most factors, and the relative unimportance of genetical and other familial factors in the variation of factors I, II and XI. The difficulties of interpretation of the genetical component of variation of the other factors are discussed.

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