PHOTOACTIVE TERTHIOPHENES: THE INFLUENCE OF SERUM ON ANTI‐HIV (HUMAN IMMUNODEFICIENCY VIRUS) ACTIVITIES
- 1 December 1994
- journal article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 60 (6) , 591-593
- https://doi.org/10.1111/j.1751-1097.1994.tb05153.x
Abstract
‐A number of carboxylic acid derivatives of the photoactive terthiophene, α‐terthienyl, were found to possess impressive UVA‐dependent activity against the human immunodeficiency virus, HIV‐1; but only when assayed in the absence of serum, indicating that the latter contained interfering components. Good antiviral activity required a high rate of singlet oxygen production, in accordance with previous observations on thiophenes.Keywords
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