IMMUNOGLOBULIN CONCENTRATIONS IN PATIENTS WITH A HISTORY OF FEBRILE CONVULSIONS PRIOR TO THE DEVELOPMENT OF EPILEPSY

Publisher Website
Google Scholar
Abstract
Serum IgA levels may be depressed in patients with epilepsy. Children with epilepsy and a previous history of febrile convulsions are especially prone to IgA depression. Serum Ig levels were determined in 25 young adults with a history of febrile convulsions and with subsequent development of epilepsy. Samples were drawn on the average 15.8 yr after the 1st febrile convulsion. Ig concentrations in serum did not differ significantly from those in a control group of patients with epilepsy and comparable regarding age, sex, type of epilepsy and drug therapy, but without previous febrile convulsions. The IgA depression in children with febrile convulsions and a subsequent diagnosis of epilepsy is presumably temporary.